Diplomate of the American College of Zoological Medicine Exam Prep
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Free DACZM Practice Questions

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Question 1

A 4-year-old Asian elephant is quieter than usual and eating less. Over 24 hours, EEHV DNA in EDTA whole blood rises from 300 to 3,000 viral genome equivalents/mL. The platelet count falls below the laboratory's reference interval, with no platelet clumping on the smear. The tongue remains pink, and no edema is present. How should these findings change management?

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Correct answer: C - Begin EEHV-directed antiviral and supportive treatment with frequent blood monitoring.

Question 2

Koi develop gill irritation after buffering raises their tank's pH from 7.4 to 8.4. Temperature remains 24°C, dissolved oxygen is adequate, and total ammonia nitrogen remains 2.0 mg/L as nitrogen. At this temperature, the un-ionized fraction is 1.31% at pH 7.4 and 11.71% at pH 8.4. The facility intervenes at 0.10 mg/L un-ionized ammonia-nitrogen (NH3-N). Compatible, conditioned, ammonia-free replacement water is available. Which current concentration and response are appropriate?

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Correct answer: A - Approximately 0.23 mg/L NH3-N; begin partial water replacement to reduce exposure.

Question 3

Aspergillus fumigatus grows from an air-sac lavage collected from a dyspneic Humboldt penguin. Endoscopy reveals pale plaques, but the clinician must distinguish invasive aspergillosis from recovery of an environmental organism. Which additional result would provide the strongest evidence of invasion?

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Correct answer: D - Hyphae penetrating the air-sac wall within areas of necrosis and granulomatous inflammation.

Question 4

A neutered male ferret with truncal alopecia, renewed sexual behavior, and an enlarged adrenal gland improves after a deslorelin implant. Follow-up ultrasonography still shows the adrenal lesion. The clinical response despite persistence of the lesion is best explained by which drug effect?

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Correct answer: B - Sustained GnRH stimulation causing pituitary receptor downregulation and reduced gonadotropin secretion.

Question 5

Several hours after a prolonged capture, a blackbuck develops a stiff gait and dark red-brown urine. Creatine kinase activity is approximately 100 times the laboratory's upper reference limit; AST activity is also markedly increased. Fresh urine is strongly positive for heme but contains almost no erythrocytes. Plasma is clear, and packed cell volume is unchanged. What unifies the laboratory findings?

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Correct answer: A - Rhabdomyolysis with myoglobinuria and release of AST from injured muscle.

Question 6

A bison dies with widespread vasculitis, and lesion testing identifies ovine herpesvirus 2. The collection also contains clinically healthy domestic sheep and wildebeest. After the affected bison is removed, management proposes changes to prevent another case. Which change targets the maintenance host of the virus identified?

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Correct answer: C - Eliminate bison exposure to domestic sheep and their secretions, including exposure to healthy sheep.

Question 7

An oxytocin order is being reviewed for an anorectic female green iguana. Serial ultrasonography shows persistent, enlarged follicles attached to both ovaries and empty oviducts. Hydration, calcium status, thermal conditions, and nesting access have been corrected without improvement. Why is oxytocin unlikely to resolve this particular lesion?

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Correct answer: B - Oviductal contractions cannot expel follicles that have not ovulated from the ovaries.

Question 8

Translocation screening of an apparently healthy endangered antelope yields a positive result. In this screening population, infection prevalence is estimated at 2%, and the assay has 90% sensitivity and 95% specificity. The animal is held separately from the destination herd. Which interpretation should guide the decision about permanently excluding it from the translocation?

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Correct answer: D - The probability of infection is about 27%; seek confirmation before permanently excluding the animal.

Question 9

Painful blubber and biopsy-confirmed fat necrosis develop in a harbor seal fed inadequately stored oily fish. Feed analysis documents substantial lipid oxidation, and the ration has not received its intended vitamin supplementation. Which deficiency-pathogenesis pairing best fits the lesion?

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Correct answer: B - Vitamin E depletion reduces the protection of cellular membrane lipids against oxidative damage.

Question 10

A newly acquired macaw has stable body weight, normal gastrointestinal transit on imaging, and no neurologic abnormalities. Two independently collected cloacal samples test positive for parrot bornavirus RNA by RT-PCR. The owner asks whether these results mean the bird has proventricular dilatation disease. Which explanation is justified?

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Correct answer: D - The results support infection but do not diagnose clinical proventricular dilatation disease.

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